Circulating microRNAs (miRNAs) from blood are increasingly recognized as biomarker candidates for human diseases.Clinical routine settings frequently include blood sampling in tubes with EDTA as anticoagulant without considering the influence of phlebotomy on the overall miRNA expression pattern.We collected blood samples from six healthy individua
Toll-like receptor (TLR) agonists demonstrate therapeutic promise as immunological adjuvants for anticancer immunotherapy.To date, AGRIMONY three TLR agonists have been approved by US regulatory agencies for use in cancer patients.Additionally, the potential of hitherto experimental TLR ligands to mediate clinically useful immunostimulatory effects
Orexin-A (a neuropeptide in the hypothalamus) plays an important role in many physiological functions, including the regulation of glucose metabolism.We have previously found that the development of post-ischemic glucose intolerance is one of the triggers of ischemic neuronal damage, which is suppressed by hypothalamic orexin-A.Other reports have s
Radiant cooling systems (RCS) are gaining acceptance as a heating, ventilation, and air conditioning (HVAC) solution for achieving adequate thermal comfort and maintaining acceptable indoor air quality inside buildings.RCS are well known for their energy-saving potential; however, serious condensation problem hinders the growth of this technology.I
If deconstruction implies a critique of the dual structures of thought, the Clothing destabilization of binaries proposed by queer theory would be the deconstructive exercise par excellence.In this case, the original pair is not destroyed; instead, their relationship is dismantled to expand its possibilities and make them more complex.This essay sh